Thiethylperazine dimaleate

Research use only, not for human use.

Thiethylperazine dimaleate is an antagonist of the D2 receptor and H1 receptor.

Thiethylperazine dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vitro):Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vivo):In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels.

Thiethylperazine could enhance the antibiotic (Vancomycin) activity at a concentration as low as 2 μg/mL. Thiethylperazine inhibits Vancomycin-sensitive E. faecalis ATCC 29212, Vancomycin-resistant E. faecalis ATCC 51299 and vancomycin-resistant E. faecalis (VREF) isolates with MIC values of 8 μg/mL, 16 μg/mL and 8 μg/mL, respectively.

Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days; young APP/PS1 mice) treatment significantly reduces Aβ42 levels in APP/PS1 mice. Animal Model:Young Aβ precursor protein (APPswe) and mutant presenilin-1 (PS1) (APP/PS1) mice Dosage:3 mg/kg Administration:Intramuscular injection; twice daily; for 30 days Result:Significantly reduced Aβ42 levels in APP/PS1 mice.

Toresten | Norzine | Thiethylperazine maleate

GPCR/G Protein

Dopamine Receptor

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1179-69-7

631.76

C30H37N3O8S2

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (197.86 mM)

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCSc1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1

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(-20℃)

With Ice Pack

≥ 2 years